Meet the Researcher: Jeri Spilberg

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Jeri Spilberg is a MSc student in the Department of Anatomy & Cell Biology at Western University. She is conducting BCC-funded breast cancer research under the mentorship of Dr. Alison Allan.

  1. Could you share your motivation/personal connection to breast cancer research?

Cancer is deeply woven into my family history, fueling my commitment to cancer research from an early age. My grandmother, a two-time breast cancer survivor, inspires me daily. While I’m incredibly grateful for her survival, I’ve made a personal promise to contribute to this field, aiming to help others facing similar challenges. Additionally, this past year my aunt was diagnosed with breast cancer. Although the prognosis is positive, the experience has further motivated me to continue learning all I can about breast cancer and hopefully contribute to cancer research. 

  1. What specific areas of breast cancer research are you currently focusing on, and why are they important?

Breast cancer can become life-threatening when cancer cells spread from the breast to other parts of the body, such as the lungs, bones, or brain – a process called metastasis. My research looks at a group of proteins called integrins, which act like tiny “grippers” on the surface of cancer cells. These grippers help cancer cells stick to their surroundings and to each other. I am studying whether these integrins help breast cancer cells spread, or metastasize to specific organs. Early results suggest that integrins might make it easier for cancer cells to break away from the primary breast tumour, spread through the body, and form metastatic tumours in different organs. By understanding how these integrins influence the spread of breast cancer, we hope to uncover new ways to block or slow down metastasis. This could support the development of better treatments and improve outcomes for people with breast cancer.

  1. What advice do you have for young individuals interested in pursuing a career in breast cancer research?

A career in research is undoubtedly challenging and full of obstacles, but when it’s driven by passion, every challenge becomes worthwhile. Perseverance is key in science, as experiments often yield unexpected results. As long as you’re genuinely interested in the work and excited to show up each day, you’ll thrive!

  1. In your opinion, what role can public awareness and advocacy play in advancing breast cancer research and treatment?

Public awareness and advocacy play a vital role in improving survival rates and advancing breast cancer research and treatment options. Early detection significantly boosts survival rates, making awareness essential. Additionally, raising public understanding about the disease highlights the importance of ongoing research, potentially increasing funding that drives further studies and leads to the discovery of new, effective treatments. 

  1. What message would you like to share with someone who has just been diagnosed with breast cancer?

Research has progressed tremendously, leading to higher and continually improving survival rates—so don’t lose hope!

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